Cefpodoxime Clavulanic Acid

ODOXICEF CV Dry SYRUP

COMPOSITION
Cefpodoxime50 MG
Clavulanic Acid31.25 MG WFI
SPECIFICATION
FORMDRY SYRUP
PACKING 1
PACKING TYPE
MRP105

DESCRIPTION

Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.

Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase. [PubChem]

SIDE EFFECTS

N/A

Gastrointestinal symptoms including stomach and abdominal pain, vomiting, and diarrhea. Rash, hyperactivity, or drowsiness have also been observed in a small number of patients

INDICATION

For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.

For use with Amoxicillin, clavulanic acid is suitable for the treatment of infections with Staph. aureus and Bacteroides fragilis, or with beta-lactamase producing H. influenzae and E. coli.

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