TAMSULOSIN

TAMLOVIB

COMPOSITION
TAMSSULOSIN0.4MG
SPECIFICATION
FORMTABLET
PACKING10×21
PACKING TYPEALU ALU
MRP

DESCRIPTION

TAMSULOSIN

Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.

 

SIDE EFFECTS

Tamsulosin

LD<sub>50</sub> = 650 mg/kg (in rats)

INDICATION

Tamsulosin

Used in the treatment of signs and symptoms of benign prostatic hyperplasia (reduction in urinary obstruction and relief of associated manifestations such as hesitancy, terminal dribbling of urine, interrupted or weak stream…etc.)