Colistimethate Sodium

COLIVIB 1 MIU

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COMPOSITION
Colistimethate Sodium1MIU
SPECIFICATION
FORMINJECTABLE
PACKING 1’s
PACKING TYPE
MRP900

DESCRIPTION

Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.

SIDE EFFECTS

Oral LD50 in rats is 5450 mg/kg. Overdosage with colistimethate can cause neuromuscular blockade characterized by paresthesia, lethargy, confusion, dizziness, ataxia, nystagmus, disorders of speech and apnea. Respiratory muscle paralysis may lead to apnea, respiratory arrest and death.

INDICATION

For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa.

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