HYDROQUINONE 2%w/w IP + TRETINOIN 0.025%w/w IP + FLUOCINOLONE ACETONIDE 0.01%w/w...

A triple combination cream used for the treatment of moderate and severe facial melasma. (Zijian Gong, 2015) Blocks the production of certain chemical messengers that make the skin red, swollen, and itchy. Suppresses the ability of melanocytes to create melanin by decreasing melanogenesis and melanocyte proliferation. (Miller-Monthrope, 2022) Promotes rapid exfoliation and stimulates collagen and elastin, which leads to smoother-looking skin. (Budzisz, 2019) The most effective topical agent for blocking melanin production through inhibition of tyrosinase enzyme in melanocytes. (Saman Ahmad Nasrollahi, 2019) Fluocinolone reduces the possible irritation or inflammation caused by tretinoin and hydroquinone, especially in sensitive skins. (Saman Ahmad Nasrollahi, 2019) Tretinoin inhibits tyrosinase enzyme, facilitates the penetration of hydroquinone, and neutralizes the stratum corneum thinning effects.(Saman Ahmad Nasrollahi, 2019) A promising therapeutic approach in reducing of pigmentation and ameliorating the quality-of-life in patients with melasma. (Saman Ahmad Nasrollahi, 2019) A safe topical agent for a range of hyperpigmentary conditions due to its ability to competitively inhibit the enzyme tyrosinase. (T Searle, 2021) A well-tolerated, safe, and efficacious cream for the treatment of moderate and severe melasma. (Zijian Gong, 2015) Promotes melanocyte destruction and the degradation of melanosomes. (Miller-Monthrope, 2022)